[1]黄 成,李 俊,马陶陶. PI3K/Akt信号通路与肝纤维化[J].中国药理学通报,2011,(08):1037-1041.
 HUANG Cheng,LI Jun,MA Tao-tao. PI3K/Akt signaling pathway and liver fibrosis[J].Chinese Pharmacological Bulletin,2011,(08):1037-1041.
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 PI3K/Akt信号通路与肝纤维化
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《中国药理学通报》[ISSN:/CN:]

卷:
期数:
2011年08期
页码:
1037-1041
栏目:
讲座与综述
出版日期:
2011-08-15

文章信息/Info

Title:
 PI3K/Akt signaling pathway and liver fibrosis
作者:
 黄 成李 俊马陶陶
 (安徽医科大学药学院,安徽合肥 230032)
Author(s):
 HUANG ChengLI JunMA Tao-tao
 (College ofPharmacy,AnhuiMedicalUniversity,Hefei 230032,China)
关键词:
 磷脂酰肌醇3激酶肝纤维化肝星状细胞增殖凋亡细胞因子
分类号:
R-05;R329.24;R329.25;R345.57;R575.202.2
文献标志码:
A
摘要:
PI3K/Akt信号通路为细胞内重要信号传导通路之一,在促进细胞增殖、抑制凋亡的过程中发挥重要作用。PI3K/Akt信号通路与肝纤维化的发生、发展密切相关。通过干预PI3K/Akt信号通路,研究肝纤维化的发病机制和药物治疗是有意义的途径。该文就PI3K/Akt信号通路的构成、转导途径及其在肝纤维化中的作用作一综述。

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备注/Memo

备注/Memo:
收稿日期:2011-04-11,修回日期:2011-05-24
基金项目:国家自然科学基金资助项目(No30873081,81072686)
作者简介:黄 成(1973-),男,博士生,E-mail:hcmail1955@sohu.com;
李 俊(1960-),男,博士,教授,博士生导师,研究方向:抗炎免疫及临床药理学,通讯作者,E-mail:lijun@ahmu.edu.cn
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