[1]杨永玉,胡长平.肥胖与脂肪组织重构[J].中国药理学通报,2016,(01):9-13.[doi:10.3969/j.issn.1001-1978.2016.01.003]
 YANG Yong-Yu,HU Chang-Ping.Obesity and adipose tissue remodeling[J].Chinese Pharmacological Bulletin,2016,(01):9-13.[doi:10.3969/j.issn.1001-1978.2016.01.003]
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肥胖与脂肪组织重构()
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《中国药理学通报》[ISSN:/CN:]

卷:
期数:
2016年01期
页码:
9-13
栏目:
讲座与综述
出版日期:
2016-01-15

文章信息/Info

Title:
Obesity and adipose tissue remodeling
文章编号:
1001-1978(2016)01-0009-05
作者:
杨永玉12胡长平1
1.中南大学药学院药理学系,湖南 长沙 410078; 2.中南大学湘雅二医院药学部,湖南 长沙 410011
Author(s):
YANG Yong-Yu12 HU Chang-Ping1
1.Dept of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China; 2.Dept of Pharmacy, Second Xiangya Hospital, Central South University, Changsha 410011, China
关键词:
肥胖 脂肪组织重构 细胞外基质 血管新生 炎症 代谢健康型肥胖
Keywords:
obesity adipose tissue remodeling extracellular matrix angiogenesis inflammation metabolically healthy obese
分类号:
R-05; R329.52; R364.3; R364.5; R589.2
DOI:
10.3969/j.issn.1001-1978.2016.01.003
文献标志码:
A
摘要:
肥胖是糖尿病、动脉粥样硬化、高脂血症和癌症发生发展的主要危险因素。肥胖发生时伴随着脂肪组织的重构,主要表现为各种细胞组成和功能的改变、血管新生、细胞外基质重构和炎症细胞浸润。深入研究脂肪组织重构对肥胖的防治具有重要意义。该文就肥胖发生时脂肪组织重构的最新研究进展进行综述。
Abstract:
Obesity is a major risk factor for the generation and development of diabetes, atherosclerosis, hyperlipidemia and cancer. Obesity is accompanied with remodeling of adipose tissue, such as changed cell component and function, angiogenesis, extracellular matrix remodeling and infiltration of inflammatory cells. It is important for the prevention of obesity to study adipose tissue remodeling. This review summarizes recent advances in adipose tissue remodeling.

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备注/Memo

备注/Memo:
基金项目:湖南省研究生创新课题(No CX2012B078) 作者简介:杨永玉(1985-),男,博士,研究方向:肥胖与代谢性疾病,E-mail: yongyuyang@126.com; 胡长平(1969-),男,博士,教授,博士生导师,研究方向:心血管药理学、呼吸药理学,通讯作者,E-mail: huchangping@yahoo.com
更新日期/Last Update: 2016-01-15