[1]彭蕾,薛仁宇,顾振纶,等.冬凌草甲素对人肺腺癌细胞株SPCA1增殖和凋亡的影响[J].中国药理学通报,2010,(04):558-559.
 PENG Lei,XUE Ren yu,GU Zhen lun,et al.The inhibitory and apoptosis effect of Oridonin on human lung adenocarcinoma SPCA1[J].Chinese Pharmacological Bulletin,2010,(04):558-559.
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冬凌草甲素对人肺腺癌细胞株SPCA1增殖和凋亡的影响()
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《中国药理学通报》[ISSN:/CN:]

卷:
期数:
2010年04期
页码:
558-559
栏目:
研究简报
出版日期:
2010-04-25

文章信息/Info

Title:
The inhibitory and apoptosis effect of Oridonin on human lung adenocarcinoma SPCA1
作者:
彭蕾12薛仁宇1顾振纶2蒋小岗2郭次仪2
1.苏州大学生物化学与分子生物学教研室,江苏 苏州215123;2.苏州中药研究所,江苏 苏州215007
Author(s):
PENG Lei12XUE Renyu1GU Zhenlun2JIANG Xiaogang2GUO Ciyi2
1.Dept of Biochemistry and Molecular Biology of Suchoow University,Suzhou Jiangsu215123,China;2.Suzhou Institute of Chinese Materia Medica,Suzhou Jiangsu215007,China
关键词:
冬凌草甲素肺癌细胞凋亡周期阻滞bcl2p21Bax
Keywords:
oridoninlung cancerapoptosiscycle arrestbcl2p21Bax
分类号:
R 284.1;R 329.24;R 329.25
文献标志码:
A

参考文献/References:

[1]Chen J H,Wang S B,Chen D Y,et al.The inhibitory effect of oridonin on the growth of fifteen human cancer cell lines[J].Chin J Clni Oncol,2007,4(1):16-20.
[2]张春玲,吴立军,左海军,等.冬凌草甲素通过改变Bax/BclxL表达激活caspase3诱导A375S2细胞凋亡[J].中国药理学通报,2004,20(6):669-72.
[2]Zhang C L,Wu L J,Zuo H J,et al.oridonin induced A375S2 cell apoptosis through caspase3 pathway after altered expression of Bax/BclxL[J].Chin Phamacol Bull,2004,20(6) :669-72.
[3]Evan G I,Vousden K H.Proliferation,cell cycle and apoptosis in cancer[J].Nature,2001,411(6835):342-50.
[4]陈英玉,潘云苓,郑志宏,等.志苓胶囊对小细胞肺癌细胞株NCIH446细胞凋亡及hTERT、CD44表达的影响[J].中国药理学通报,2008,24(10):1382-6.
[4]Chen Y Y,Pan Y L,Zheng Z H,et al.Effets of Zhiling capsule on apoptosis and expression of hTERT,CD44 in small cell lung cancer cell line NCIH446[J].Chin Phamacol Bull,2008,24(10):1382-6.
[5]宋其蔓,孙洞箫.细胞凋亡与p21关系的研究进展[J].医学综述,2008,14(6):816-8.
[5]Song Q M,Sun D X.Advancement in researches on relationship between apoptosis and p21[J].Med Recap,2008,14(6):816-8.

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备注/Memo

备注/Memo:
收稿日期:2010-01-04,修回日期:2010-02-01基金项目:香港保健协会资助项目(No 20070902)作者简介:彭蕾(1985-),女,硕士生,研究方向:肺癌发病机制及药物治疗,Email:pengleicoco@gamil.com;薛仁宇(1963-),男,副教授,硕士生导师,研究方向:生物化学与分子生物学,通讯作者,Tel:051265880183,Email:xuery@suda.edu.cn
更新日期/Last Update: 2010-04-25