[1]张业昊,姚明江,刘建勋.缺血性脑血管病的现代研究进展[J].中国药理学通报,2019,(09):1185-1188.[doi:10.3969/j.issn.1001-1978.2019.09.001]
 ZHANG Ye-hao,YAO Ming-jiang,LIU Jian-xun.Advances in modern research on ischemic cerebrovascular diseases[J].Chinese Pharmacological Bulletin,2019,(09):1185-1188.[doi:10.3969/j.issn.1001-1978.2019.09.001]
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缺血性脑血管病的现代研究进展()
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《中国药理学通报》[ISSN:/CN:]

卷:
期数:
2019年09期
页码:
1185-1188
栏目:
讲座与综述
出版日期:
2019-09-09

文章信息/Info

Title:
Advances in modern research on ischemic cerebrovascular diseases
文章编号:
1001-1978(2019)09-1185-04
作者:
张业昊姚明江刘建勋
中国中医科学院西苑医院基础医学研究所,中药药理北京市重点实验室,北京 100091
Author(s):
ZHANG Ye-hao YAO Ming-jiang LIU Jian-xun
Institute of Basic Medical Sciences of Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing Key Lab of Chinese Materia Pharmacology, Beijing 100091, China
关键词:
缺血性脑血管病 microRNA 代谢组学 炎性 神经保护 研究进展
Keywords:
ischemic cerebrovascular disease microRNA metabolomics inflammatory neuroprotection advances
分类号:
R322.81; R342.2; R364.5; R743.3; R743.31
DOI:
10.3969/j.issn.1001-1978.2019.09.001
文献标志码:
A
摘要:
脑卒中是一种常见的脑血管疾病,其中绝大多数脑卒中病例是由短暂性或永久性脑血管闭塞引起的缺血性脑血管病(缺血性中风),具有分辨率高、致残率高、死亡率高的特点。目前,在临床实践中已经研究出许多策略用于改善缺血性中风的脑部抢救和恢复,包括抗氧化策略、神经元保护策略、抗炎策略等。进一步探究缺血性中风的病理机制及寻找有效的药物,是目前亟需解决的问题。该文简要总结近年来对于缺血性脑血管病的最新研究进展,为未来临床治疗及研究提供思路。
Abstract:
Stroke is a common disease; the vast majority of stroke cases are caused by transient or permanent cerebrovascular occlusion of ischemic cerebrovascular disease(ischemic stroke), which eventually leads to cerebral infarction.Many strategies have been studied in clinical trials to improve brain rescue and recovery for ischemic stroke, including antioxidant strategies, neuronal protection strategies, and even anti-inflammatory strategies.Therefore, it is an urgent problem to explore the pathologic mechanism of ischemic stroke and find effective drugs.In this paper, the recent advances in the study of ischemic cerebrovascular diseases are briefly summarized to provide ideas for future research.

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备注/Memo

备注/Memo:
收稿日期:2019-05-10,修回日期:2019-06-19
基金项目:国家重点基础研究发展计划资助项目(No 2015CB554405)
作者简介:张业昊(1989-),女,博士,研究方向:脑血管药理学,E-mail: zyh322@163.com;
刘建勋(1955-),男,博士,研究员,研究方向:中药药理学,通讯作者,E-mail: liujx0324@sina.com
更新日期/Last Update: 2019-08-14